4-(4-Hydroxyphenyl)butanoic acid

Name	4-(4-Hydroxyphenyl)butanoic acid
Synonyms	4-(4-HYDROXYPHENYL)B 4-Carboxypropylphenol P-HYDOROXYPHENYLBUTANOIC ACID 4-Hydroxy-benzenebutanoic acid 4-(4-HYDROXYPHENYL)BUTYRIC ACID benzenebutanoic acid, 4-hydroxy- 4-(4-Hydroxyphenyl)butanoic acid Benzenebutanoic acid, 4-hydroxy- 4-(4-HYDROXYPHENYL)BUTANOIC ACID
CAS	7021-11-6
InChI	InChI=1/C10H12O3/c11-9-6-4-8(5-7-9)2-1-3-10(12)13/h4-7,11H,1-3H2,(H,12,13)

Molecular Formula	C10H12O3
Molar Mass	180.2
Density	1.214±0.06 g/cm3(Predicted)
Melting Point	110-111 °C
Boling Point	128-200 °C(Press: 0.4 Torr)
Flash Point	188.3°C
Solubility	Chloroform (Slightly), DMSO (slightly)
Vapor Presure	6.03E-06mmHg at 25°C
Appearance	Solid
Color	White to Off-White
pKa	4.78±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.567

use	4-(4-hydroxyphenyl) butyric acid is an organic synthesis intermediate and Pharmaceutical intermediates can be used in laboratory research and development processes and chemical and pharmaceutical synthesis processes.
preparation	4-(4-methoxyphenyl) butyric acid (25g,129mmol) was dissolved in 48% HBr(125ml) and AcOH(125ml). The resulting solution was heated overnight at 150°C. The resulting mixture was vacuum concentrated and the residue dissolved in EtOAc(500ml). The solution was washed with water (500ml), dried (MgSO4) and concentrated to give 4-(4-hydroxy-phenyl)-butyric acid, a brown solid.

Last Update：2024-04-09 21:11:58